Statistical Methods for QTL Mapping

Biological Background A Brief Sketch of the History of Genetics and Mendel's Pea Plant Experiments Basic Elements of Genetics Cell Division, Crossover and Recombination Gene Expression Genetic Maps and Mapping Functions Experimental Crosses Selected Topics in Statistics Population and Distribution Random Variable, Samples, Statistics and Related Distribution Estimation Hypothesis Testing Linear and Generalized Linear Models Mixture Models and EM Algorithm Bayesian Analysis Samplers for Markov Chain Monte Carlo Simulation An Overview on Feature Selection with Small-n-large-p Models Model Selection Criteria for Small-n-large-p Models Quantitative Genetics and General Issues on QTL Mapping Distributional Features of Genetic Quantitative Traits Genetic Values and Variances Statistical Models with Known QTL Genotypes Conditional Probabilities of Putative QTL Genotypes Given Markers QTL Mapping Data One-Dimensional Mapping Approaches QTL Mapping by Single-Marker Analysis Single Interval Mapping Composite Interval Mapping Determination of Threshold Values Determination of Sample Sizes Selective Genotyping Multiple Interval Mapping Gaussian Mixture Models for QTL Mapping An EM Algorithm for Gaussian Mixture Models Mixture Generalized Linear Models General EM Algorithms for Mixture Generalized Linear Models Multiple Interval Mapping Procedures Example: The Analysis of Radiata Pine Data Multiple Interval Mapping with Polytomous Traits Multiple Interval Mapping of Traits with Spike Distributions QTL Mapping with Dense Markers Feature Selection Methods for QTL Mapping QTL Mapping with Consideration of QTL Epistatic Effects Bayesian Approach to QTL Mapping The Framework of the Bayesian Approach to QTL Mapping Bayesian QTL Mapping with Inbred Line Cross Data Bayesian QTL Mapping for Outbred Offsprings Bayesian QTL Mapping for Ordinal Polytomous Traits Multi-Trait QTL Mapping and eQTL Mapping Multi-Trait QTL Mapping I: Single-QTL Model Approaches Multi-Trait QTL Mapping II: Multi-QTL Model Approaches eQTL Mapping Approaches Bibliography Index

9781439868300

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