FUNCTIONAL TISSUE ENGINEERING

Part I. The Functional Properties of Native Tissues * How Does Nature Build a Tissue? * Ligament Healing: Present Status and the Future of Functional Tissue Engineering * Native Properties of Cardiovascular Tissues: Guidelines for Functional Tissue Engineering * Functional Properties of Native Articular Cartilage * Excitability and Contractility of Skeletal Muscle: Measurements and Interpretations * Part II. Functional Requirements of Engineered Tissues * Functional Requirements for the Engineering of a Blood Vessel Substitute * In vivo Force and Strain of Tendon, Ligament and Capsule * Requirements for Biological Replacement of the Articular Cartilage at the Knee Joint * Functional Requirements: Cartilage * Part III. Design Parameters for Tissue Engineering * Design Parameters for Functional Tissue Engineering * Tissue Engineering a Heart: Critical Issues * Design Parameters for Engineering Bone Regeneration * Tissue Engineering of Bone: The Potential Uses of Gene Therapy for Difficult Bone Loss Problems * Engineered Skeletal Muscle: Functional Tissues, Organs and Interfaces * Bioengineering the Growth of Articular Cartilage * Part IV. Assessment of Function in Engineered Tissues * Functional Tissue Engineering: Assessment of Function in Tendon and Ligament Repair * The Role of Mechanical Forces in Tissue Engineering of Articular Cartilage * Biomechanics of Native and Engineered Heart Valves * Assessment of Function in Tissue Engineered Vascular Grafts * Assessment of the Performance of Engineered Tissues in Humans Requires the Development of Highly Sensitive and Quantitative Non-invasive Outcome Measures * Part V. Cell-matrix Interactions in Functional Tissue Engineering * The Biomechanics of Cell-matrix Interactions in Tissue Engineering * Regulation of Cellular Response to Mechanical Signals by Matrix Design * Artificial Soft Tissue Fabrication from Cell-contracted Biopolymers * Cytomechanics: Signaling to Mechanical Load in Connective Tissue Cells and Role in Tissue Engineering * Part VI. Bioreactors and the Role of Biophysical Stimuli in Tissue Engineering * The Role of Biomechanics in Analysis of Cardiovascular Diseases: Regulation of the Fluid Shear Response by Inflammatory Mediators * A Full Spectrum of Tissue Engineered Blood Vessels: From Macroscopic to Microscopic * Engineered Functional Cartilage and Cardiac Tissue: In vitro Culture Parameters * Tissue Engineered Skeletal Muscle * Part VII. Regulatory and Clinical Issues in Tissue Engineering * From Concept Towards the Clinic: Preclinical Evaluation of Tissue Engineered Constructs * Trends in the FDA

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