No products in the cart.
Protein Interaction Networks: Computational Analysis
Original price was: ₹6,568.62.₹5,254.90Current price is: ₹5,254.90.
ISBN: 9780521888950
Author/Editor: Aidong Zhang
Publisher: Cambridge University Press
Year: 2009
1 in stock (can be backordered)
Description
The analysis of protein-protein interactions is fundamental to the understanding of cellular organization, processes, and functions. Proteins seldom act as single isolated species; rather, proteins involved in the same cellular processes often interact with each other. Functions of uncharacterized proteins can be predicted through comparison with the interactions of similar known proteins. Recent large-scale investigations of protein-protein interactions using such techniques as two-hybrid systems, mass spectrometry, and protein microarrays have enriched the available protein interaction data and facilitated the construction of integrated protein-protein interaction networks. The resulting large volume of protein-protein interaction data has posed a challenge to experimental investigation. This book provides a comprehensive understanding of the computational methods available for the analysis of protein-protein interaction networks. It offers an in-depth survey of a range of approaches, including statistical, topological, data-mining, and ontology-based methods. The author discusses the fundamental principles underlying each of these approaches and their respective benefits and drawbacks, and she offers suggestions for future research.
Additional information
Weight | 0.55 kg |
---|
Product Properties
Year of Publication | 2009 |
---|---|
Table of Contents | 1. Introduction; 2. Experimental approaches to generation of protein-protein interaction data; 3. Computational methods for the prediction of protein-protein interactions; 4. Basic properties and measurements of protein interaction networks; 5. Modularity analysis of protein interaction networks; 6. Topological analysis of protein interaction networks Woo-chang Hwang; 7. Distance-based modularity analysis; 8. Graph-theoretic approaches to modularity analysis; 9. Flow-based analysis of protein interaction networks; 10. Statistics and machine learning based analysis of protein interaction networks Pritam Chanda and Lei Shi; 11. Integration of gene ontology into the analysis of protein interaction networks Young-rae Cho; 12. Data fusion in the analysis of protein interaction networks; 13. Conclusion. |
Author | Aidong Zhang |
ISBN/ISSN | 9780521888950 |
Binding | Hardback |
Edition | 1 |
Publisher | Cambridge University Press |
You must be logged in to post a review.
Reviews
There are no reviews yet.