Epigenetics for Drug Discovery

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ISBN: 9781849738828
Author/Editor: Nessa Carey

Publisher: Royal Society of Chemistry

Year: 2016

1 in stock (can be backordered)

SKU: ABD-RSC-4842 Category:

Description

1. Epigenetics for drug discovery and drug development

2.Epigenetics is one of the fastest moving fields in drug discovery

3. Medicinal chemists in industrey and academia, pharmaceutical industry

4. Issues in Toxicology Series, MedChemComm

5. Epigenetic drug discovery involves targetting enzymes responsible for histone modification, to modify gene expression.

Additional information

Weight 0.653 kg

Product Properties

Year of Publication

2016

Table of Contents

Epigenetics - What it is and Why it Matters; Enzyme and Protein Families that Regulate Histone Modifications and Crosstalk; Epigenetics and Disease; Targeting DNA Methylation; Targeting Histone Acetylation; Targeting Histone Lysine Methyltransferases in Cancer; Targeting Non-Acetylation Histone Erasers; Progress in Targeting Epigenetic Readers; Who will Bebefit from Epigenetic Drugs; Dosing - When Less Is More; Histone Methyltransferase Activity Assays; Safety Considerations for Epigenetic Mechanisms as Drug Targets: Are Existing Toxicology Studies Fit for Purpose?;

Author

Nessa Carey

ISBN/ISSN

9781849738828

Binding

Hardback

Edition

1

Publisher

Royal Society of Chemistry

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